Author

M. W. Clarkson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Kern· 1 shared D. Mavor· 1 shared D. S. Tawfik· 1 shared J. S. Fraser· 1 shared L. Liu· 1 shared L. R. Kenner· 1 shared R. Otten· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

D. Kern

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1 paper

Recent·Most cited

Rescue of Conformational Dynamics in Enzyme Catalysis by Directed Evolution

R. Otten, L. Liu, L. R. Kenner, M. W. Clarkson, D. Mavor, D. S. Tawfik, D. Kern, J. S. Fraser

This study uses directed evolution to identify mutations that restore catalytic activity in a mutant enzyme, revealing how conformational dynamics are shaped by evolutionary selection.

bioRxiv · Sep 5, 2017Biophysics