Author

D. Mavor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

D. N. A. Bolon· 2 shared J. M. Flynn· 2 shared A. Rossouw· 1 shared C. Bank· 1 shared C. Hollins· 1 shared C. J. P. Mathy· 1 shared D. Kern· 1 shared D. S. Tawfik· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

D. N. A. Bolon

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Author profile →

3 papers

Recent·Most cited

A complete allosteric map of a GTPase switch in its native network

C. J. P. Mathy, P. Mishra, J. M. Flynn, T. Perica, D. Mavor, D. N. A. Bolon, T. Kortemme

The paper systematically identifies new allosteric regulatory sites in Gsp1/Ran by mutational scanning, revealing that many deleterious mutations affect function outside the active site through allosteric coupling.

bioRxiv · Apr 13, 2022Biophysics

Comprehensive fitness maps of Hsp90 show widespread environmental dependence

J. M. Flynn, A. Rossouw, P. A. Cote-Hammarlof, I. Fragata, D. Mavor, C. Hollins, C. Bank, D. N. A. Bolon

This study maps the fitness effects of Hsp90 variants across multiple environments, showing widespread environmental dependence and selection for robustness.

bioRxiv · Dec 9, 2019Evolutionary Biology

Rescue of Conformational Dynamics in Enzyme Catalysis by Directed Evolution

R. Otten, L. Liu, L. R. Kenner, M. W. Clarkson, D. Mavor, D. S. Tawfik, D. Kern, J. S. Fraser

This study uses directed evolution to identify mutations that restore catalytic activity in a mutant enzyme, revealing how conformational dynamics are shaped by evolutionary selection.

bioRxiv · Sep 5, 2017Biophysics