Insulation of ribosomal promoter activity by Fis, H-NS or a divergent promoter within the packed E. coli genome.
E. Brambilla, M. Yousuf, Q. Zhang, G. Mbemba, C. Oeuvray, D. Mektepbayeva, A. Olliver, M. C. Lagomarsino, B. Sclavi
The paper shows that Fis and H-NS insulation mechanisms and divergent promoters help regulate ribosomal promoter activity in E. coli, allowing gene duplication without local genomic effects.
bioRxiv · Mar 27, 2024 · PreprintCell Biology