Single-cell RNA-seq reveals TCR clonal expansion and a high frequency of transcriptionally distinct double-negative T cells in NOD mice
M. Z. Islam, S. Zimmerman, J. Weidanz, J. Ordovas-Montanes, M. Robben, J. Luber, A. D. Kostic
This study uses single-cell RNA-seq to analyze T cell populations in NOD mice, identifying clonal expansion and transcriptionally distinct double-negative T cells associated with T1D progression.
bioRxiv · Jul 21, 2023 · PreprintImmunology