Author

A. D. Kostic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:clustering· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Zimmerman· 2 shared B. Nguyen· 1 shared B. Tierney· 1 shared C. J. Patel· 1 shared J. Luber· 1 shared J. Ordovas-Montanes· 1 shared J. Weidanz· 1 shared L.-D. Pham· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

S. Zimmerman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell RNA-seq reveals TCR clonal expansion and a high frequency of transcriptionally distinct double-negative T cells in NOD mice

M. Z. Islam, S. Zimmerman, J. Weidanz, J. Ordovas-Montanes, M. Robben, J. Luber, A. D. Kostic

This study uses single-cell RNA-seq to analyze T cell populations in NOD mice, identifying clonal expansion and transcriptionally distinct double-negative T cells associated with T1D progression.

bioRxiv · Jul 21, 2023 · PreprintImmunology

Quantifying shared and unique gene content across 17 microbial ecosystems

S. Zimmerman, B. Tierney, C. J. Patel, A. D. Kostic

The paper quantifies shared and unique gene content across 17 microbial ecosystems, revealing most genes are unique and only 1,864 genes are present in all metagenomes.

bioRxiv · Jul 19, 2022Microbiology

The impact of multigenerational high-fat diet feeding on the gut microbiome and host metabolism

M. C. Wibowo, Z. Yang, T. A. Chavkin, B. Nguyen, L.-D. Pham, T. L. Huang, M. D. Lynes, Y.-H. Tseng, A. D. Kostic

This study shows that multigenerational high-fat diet feeding in mice leads to improved metabolic health through microbiome adaptation, with leaner mice passing on resistance to obesity.

bioRxiv · Feb 1, 2022 · PreprintMicrobiology