GLI3 Processing by the Primary Cilium Regulates Muscle Stem Cell Entry into GAlert
C. Brun, M.-C. Sincennes, A. Y. T. Lin, D. Hall, W. Jarassier, P. Feige, M. Ritso, F. Le Grand, M. A. Rudnicki
This study shows that GLI3 processing by primary cilia maintains satellite cell dormancy and that its absence leads to premature activation and enhanced regenerative capacity.
bioRxiv · Dec 7, 2020 · PreprintCell Biology