Single-Cell Map of Diverse Immune Phenotypes in the Metastatic Brain Tumor Microenvironment of Non Small Cell Lung Cancer
L. Wang, J. Dai, R.-R. Han, L. Dong, D. Feng, G. Zhu, W. Guo, Y. Wang, M. Chao, M.-Z. Jin, S.-J. Jin, D.-P. Wei, W. Sun, W.-L. Jin
The paper uses single-cell RNA sequencing to analyze immune cell composition in brain metastases of NSCLC patients, finding reduced T cell activity and expanded M2-polarized tumor-associated macrophages.
bioRxiv · Dec 30, 2019Cancer Biology