A dynamic RNA hub facilitates activation induced cytidine deaminase recruitment to the immunoglobulin heavy chain locus
Mariia Mikhova, Mackenzie Kapanka, Li Han, Gergely Ungor, Jens C. Schmidt, Kefei Yu
The paper shows that a dynamic RNA hub formed by nascent switch region transcripts facilitates AID recruitment to the IgH locus, driving class switch recombination.
Molecular Cell · Jun 23, 2026Peer-reviewedCell Biology