Author

Maclaine Parish

University of Michigan

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Genetics· 1

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Approach:experimental assay· 1 Organism:yeast· 1

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Anthony AntonellisiD· 1 shared Kira E. Jonatzke· 1 shared Molly E. KuoiD· 1 shared

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2024-2024 · peak 1/yr

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Anthony AntonellisORCID

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1 paper

Recent·Most cited

Comprehensive assessment of recessive, pathogenic AARS1 alleles in a humanized yeast model reveals loss-of-function and dominant-negative effects

Molly E. Kuo, Maclaine Parish, Kira E. Jonatzke, Anthony Antonellis

The paper evaluates AARS1 variants in a humanized yeast model, finding loss-of-function effects and identifying a variant with both recessive and dominant-negative effects.

bioRxiv · Jun 20, 2024 · PreprintGenetics