Droplet-based Random Barcode Transposon-site Sequencing (Droplet RB-TnSeq) to characterize phage-host interactions
Fangchao Song, Allison Hung, Madeline L. Moore, Vivek K. Mutalik, Adam P. Arkin
The paper introduces Droplet RB-TnSeq to study phage-host interactions by isolating single mutant cells with defined phage titers, identifying host factors beyond receptor-level interactions.
bioRxiv · Sep 29, 2025 · PreprintMicrobiology