SGEF coordinates epithelial morphogenesis by regulating junction stability, collective migration, and extracellular matrix remodeling
Madeline Lovejoy, Agustín Rabino, Lucia Gonzalez-Blotta, Vennela Gangasani, Sophia M Durham, Gabriel Kreider-Letterman, Rafael García‐Mata
This study shows SGEF regulates epithelial morphogenesis by maintaining junction stability, actomyosin organization, and extracellular matrix remodeling during 3D cyst development.
bioRxiv · Jul 20, 2026 · PreprintCell Biology