Rafael García‐Mata

The paper develops a FRET biosensor to visualize RhoG activity in live cells and shows its spatial relationship with Rac1 during protrusion.

This study shows SGEF regulates epithelial morphogenesis by maintaining junction stability, actomyosin organization, and extracellular matrix remodeling during 3D cyst development.

This study uses an ex vivo hindlimb culturing platform with dynamic mechanical loading and PNCOL injection to enhance muscle regeneration and reduce inflammation in critical-size TA muscle defects.

The paper presents techniques to quantify the horizontal and vertical distribution of junctional proteins in fixed epithelial cells under different experimental conditions.

This study identifies a novel signaling pathway involving the Scribble/SGEF/Dlg1 complex that regulates apical junction stability, ZO-1 expression, and E-cadherin dynamics in epithelial cells.