Amyloid precursor protein. An Achilles heel to exploit in the treatment of prostate cancer
Mai Alhadrami, Emily Gill, Claire M. Perks, Rachel M. Barker
This study shows that amyloid precursor protein (APP) is upregulated in prostate tumors and critical for cancer cell survival through interactions with androgen and IGF-I signaling, suggesting potential for repurposing AD drugs in prostate cancer treatment.
bioRxiv · Sep 22, 2026 · PreprintCancer Biology