Author

Rachel M. Barker

University of BristolORCID 0000-0003-0309-2708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Claire M. PerksiD· 1 shared Emily GilliD· 1 shared Mai Alhadrami· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Claire M. PerksORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 22, 2026

Amyloid precursor protein. An Achilles heel to exploit in the treatment of prostate cancer

Mai Alhadrami, Emily Gill, Claire M. Perks, Rachel M. Barker

This study shows that amyloid precursor protein (APP) is upregulated in prostate tumors and critical for cancer cell survival through interactions with androgen and IGF-I signaling, suggesting potential for repurposing AD drugs in prostate cancer treatment.

DOI 10.64898/2026.09.21.752657

humanprotein structure

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