KIRA6 is an effective and versatile mast cell inhibitor of IgE-mediated activation
Veronika Wunderle, Thomas Wilhelm, Shatha Boukeileh, Jonas Goßen, Michael A. Margreiter, Roman Sakurov, Sandro Capellmann, Maike Schwoerer, Nabil Ahmed, Gina Bronneberg, Michel Arock, Christian Martin, Thomas Schubert, Francesca Levi‐Schaffer, Giulia Rossetti, , Michael Huber
This study identifies KIRA6 as a dual inhibitor of LYN and FYN that suppresses IgE-mediated mast cell activation and inflammation.
bioRxiv · Apr 18, 2024Immunology