A flow cytometry-based assay to quantify the binding of transmembrane ligands to their cognate receptors using fluorescent virus-like particles
Colin Kim, Maira Gaballa, Danyel Lee, Emmanuelle Jouanguy, Shen‐Ying Zhang, Jean‐Laurent Casanova, Ahmad Yatim
This paper introduces a flow cytometry-based assay using fluorescent virus-like particles to quantify transmembrane ligand-receptor binding, showing it can study patient-derived variants and enable single-cell analysis of multiple interactions.
BIO-PROTOCOL · Jan 1, 2026Peer-reviewedCell Biology