Author

Danyel Lee

Hôpital Necker-Enfants MaladesORCID 0000-0003-3124-0245Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jean‐Laurent CasanovaiD· 2 shared Ahmad YatimiD· 1 shared Alison W. AshbrookiD· 1 shared Ana PinharandaiD· 1 shared Ansgar F. StenzeliD· 1 shared Aurélie CobatiD· 1 shared Avery PeaceiD· 1 shared Brandon S. RazookyiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Jean‐Laurent CasanovaORCID

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2 papers

Recent·Most cited

Cell BiologyBIO-PROTOCOLPeer-reviewedJan 1, 2026

A flow cytometry-based assay to quantify the binding of transmembrane ligands to their cognate receptors using fluorescent virus-like particles

Colin Kim, Maira Gaballa, Danyel Lee…·Ahmad Yatim

This paper introduces a flow cytometry-based assay using fluorescent virus-like particles to quantify transmembrane ligand-receptor binding, showing it can study patient-derived variants and enable single-cell analysis of multiple interactions.

DOI 10.21769/bioprotoc.5726

humanflow cytometry

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ImmunologyPLoS BiologyPeer-reviewedSep 24, 2024

A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

Jérémie Le Pen, Gabrielle Paniccia, Volker Kinast…·Charles M. Rice

The paper identifies PLSCR1 as a host factor restricting SARS-CoV-2 entry, which recent variants have evolved to bypass, through a CRISPR screen and integration of genetic studies.

20 citationstop 3%

humangenetic perturbation / CRISPR

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