An essential role for glial cells in postingestive nutrient sensing
Divita Kulshrestha, Charlotte Koch, Majid Khalilov, Stefanie Schirmeier
The paper shows that glial cells convert glucose and sorbitol into fructose via the polyol pathway, which is then sensed by neurons expressing Gr43a to drive behavioral adaptation.
bioRxiv · Jul 26, 2024 · PreprintNeuroscience