CYB5R3 Controls Sex-Specific Stress Erythropoiesis via Heme-Biosynthesis
Fabliha Ahmed Chowdhury, Malini Sharma, Katherine C. Wood, Sarah A Saad, Shuai Sammy Yuan, Megan P. Miller, Scott A. Hahn, Máté Katona, Stefanie N. Taiclet, Sonia R. Salvatore, Francisco Jose Schopfer, Adam C. Straub
This study shows CYB5R3 is essential for stress-induced erythropoiesis, with stronger effects in males, and reveals its role in heme biosynthesis and erythroid differentiation.
bioRxiv · Dec 5, 2025 · PreprintMolecular Biology