Scott A. Hahn

Mitoregulin supports mitochondrial membrane integrity and protects against cardiac ischemia-reperfusion injury

This study shows that Mitoregulin (Mtln) protects mitochondrial membrane integrity and reduces cardiac ischemia-reperfusion injury by stabilizing cardiolipin and preventing membrane damage.

CYB5R3 Controls Sex-Specific Stress Erythropoiesis via Heme-Biosynthesis

This study shows CYB5R3 is essential for stress-induced erythropoiesis, with stronger effects in males, and reveals its role in heme biosynthesis and erythroid differentiation.

Endothelial CYB5R3 couples store-operated calcium entry to TRPV2 activation and vascular fitness

This paper identifies CYB5R3 as a redox switch that couples store-operated calcium entry to TRPV2 activation, enhancing vascular function through NO-dependent oxidative inhibition of PTPN1.

CYB5R4 sustains endothelial proliferation and ischemia-induced angiogenesis by maintaining RRM2-dependent nucleotide balance

This study identifies CYB5R4 as a regulator of endothelial proliferation and ischemia-induced angiogenesis through RRM2-dependent nucleotide balance.

Development of an Open-source Low-cost Pressure Myography and Cardiac Flow Simulator, HemoLens, for Mechanical Characterization of Native and Engineered Blood Vessels

The paper develops HemoLens, a low-cost open-source pressure myography system for characterizing vascular mechanics in native and engineered blood vessels.