Epigenetics biomarkers of delirium: immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients
Taku Saito, Hiroyuki Toda, Gabrielle N. Duncan, Sydney S. Jellison, Tong Yu, Mason J. Klisares, Sophia Daniel, Allison Julie Andreasen, Lydia R. Leyden, Mandy M. Hellman, Eri Shinozaki, Sangil Lee, Aihide Yoshino, Hyunkeun R. Cho, Gen Shinozaki
The paper identifies DNA methylation differences in blood between delirium patients and non-delirium controls, highlighting immune response and cholinergic synapse pathways.
Journal of Psychiatric Research · Jun 6, 2020Peer-reviewedNeuroscience