Hiroyuki Toda

This study shows that stress-induced brain extracellular vesicles reduce anxiety in mice, and three miRNAs within these vesicles contribute to the anxiolytic effect by suppressing Mecp2 in neurons.

The paper investigates reciprocal inhibition between the amygdala and vmPFC in PTSD patients, linking attentional biases to symptom clusters and amygdala reactivity.

The paper identifies DNA methylation differences in blood between delirium patients and non-delirium controls, highlighting immune response and cholinergic synapse pathways.

The paper examines DNA methylation changes in neurotrophic genes across aging and delirium using three independent cohorts, finding positive correlations with aging and stronger associations in delirium cases.