Epilepsy and neurobehavioral abnormalities in mice with a KCNB1 pathogenic variant that alters conducting and non-conducting functions of KV2.1
Nicole A. Hawkins, Sunita N. Misra, Manuel Jurado, Seok Kyu Kang, Nicholas C. Vierra, Kimberly Nguyen, Lisa M. Wren, Alfred L. George, James S. Trimmer, Jennifer A. Kearney
This paper identifies a KCNB1 pathogenic variant in mice that causes epilepsy and neurobehavioral abnormalities, mimicking human DEE features.
Neurobiology of Disease · Oct 23, 2020Peer-reviewedNeuroscience