Preclinical and Toxicology Assessment of ISFP10, an Inhibitor of Fungal Phosphoglucomutase (PGM)
Madeline R. Pellegrino, Marc Bindzus, Theodore J. Kottom, Savita Ayyalasomayajula, Eunhee S. Yi, ANDREW HAR LIMPER
This study evaluates the safety and antifungal activity of ISFP10, a fungal PGM inhibitor, in mice, finding no toxicity and concentration-dependent growth inhibition of Candida species.
bioRxiv · Jan 7, 2025 · PreprintPharmacology & Toxicology