Precocious hippocampal structural and functional changes in gestational protein-restricted male elderly offspring: an Alzheimer-simile disease model?
Gabriel Boer Grigoletti-Lima, Marcelo Gustavo Lopes, Ana Tereza Barufi Franco, Aparecida Marcela Damico, Patrícia Aline Boer, José Antônio Rocha Gontijo
This paper investigates the effects of gestational protein restriction on hippocampal structure and function in male offspring, finding accelerated functional decline and AD-like biomarker deposition.
bioRxiv · Apr 7, 2021 · PreprintDevelopmental Biology