Gabriel Boer Grigoletti-Lima

EARLY-LIFE STRESS INDUCES SEXUALLY DIMORPHIC BRAIN AGING VIA MESOLIMBIC ALTERATIONS AND FRONTO-STRIATAL DYSFUNCTION

This study shows that prenatal stress leads to different brain aging patterns in male and female mice, affecting behavior and cognition through sex-specific mechanisms involving insulin resistance and hormonal changes.

Enriched environmental intervention mitigates hippocampal cellularity and behavioral disorders in maternal protein-restricted male rat offspring

This study shows that maternal protein restriction during pregnancy and breastfeeding reduces hippocampal neurons and behavioral issues in male rat offspring, but an enriched environment can reverse these effects.

Precocious hippocampal structural and functional changes in gestational protein-restricted male elderly offspring: an Alzheimer-simile disease model?

This paper investigates the effects of gestational protein restriction on hippocampal structure and function in male offspring, finding accelerated functional decline and AD-like biomarker deposition.