Selective Knockout of Murine Glutamic Acid-rich Protein 2 (GARP2) Significantly Alters Cellular Dark Noise in Rod Photoreceptors
Delores A. Stacks, Ulisse Bocchero, Marci L. DeRamus, Mai Nguyen, Jeffrey D. Messinger, Timothy W. Kraft, Steven J. Pittler, Johan Pahlberg
This study knocks out GARP2 in mouse rods and finds it reduces dark noise through PDE6 stabilization, affecting rod function without major structural changes.
bioRxiv · May 9, 2025 · PreprintNeuroscience