Genomic Determinants of Lethality and Therapeutic Vulnerability in Castration-Resistant Prostate Cancer
Ryan James Rebernick, Liat Hammer, Mahnoor Naseer Gondal, Abhijit Parolia, Yi‐Mi Wu, Noshad Hosseini, Matthew J. Schipper, Anbarasu Kumaraswamy, Matthew McFarlane, Xuhong Cao, Phillip Lee Palmbos, Megan E.V. Caram, David Carl Smith, Sarah Elizabeth Yentz, MI-OncoSeq Team, , Marcin Cieslik
This study identifies genomic drivers of progression and therapeutic outcomes in mCRPC and develops a multi-omic classifier to predict patient survival across multiple therapies.
bioRxiv · Jun 20, 2026 · PreprintCancer Biology