Control of spatio-temporal patterning via cell density in a multicellular synthetic gene circuit
Marco Santorelli, Pranav S. Bhamidipati, Andriu Kavanagh, Victoria A. MacKrell, Trusha Sondkar, Matt W. Thomson, Leonardo Morsut
This study shows how cell density affects signal transduction in synthetic gene circuits, enabling spatial and temporal control of multicellular patterning.
bioRxiv · Oct 4, 2022 · PreprintSynthetic Biology