Clonally expanded IgG antibody-secreting cells preferentially target influenza nucleoprotein following homologous and heterologous infections
Andreas Agrafiotis, Raphael Kuhn, Camilla Panetti, Marco Venerito, Hathaichanok Phandee, Lucas Stalder, Danielle Shlesinger, Vittoria Martinolli D’Arcy, Kai‐Lin Hong, Daphne van Ginneken, Alessandro Genovese, Nicole Joller, Annette Oxenius, Sai T. Reddy, Alexander Yermanos
The paper characterizes clonal dynamics of antibody-secreting cells in bone marrow following influenza infection, finding that IgG ASCs preferentially target nucleoprotein regardless of infection type.
The Journal of Immunology · Jul 26, 2025Peer-reviewedImmunology