Endothelial Colony-Forming Cell Transcriptomic Profiling in CT-defined Coronary Artery Disease from the BioHEART-CT Study Implicate CCBE1 in Mitochondrial Dysfunction-associated Atherosclerosis
Weiqian Eugene Lee, Sarah L. Cook, Gareth S. D. Purvis, Albert Henry, Kirsten Schnitzler, Elijah Genetzakis, Marie Besnier, Madhuvanti Chandrakanthan, Andy Tran, Dario Strbenac, Carmen Mifsud, Katharine A. Bate, Stephen Thomas Vernon, Tung V. Nguyen, Michael Patrick Gray, , Gemma Alexandra Figtree
This study identifies CCBE1 as a gene associated with mitochondrial dysfunction in atherosclerosis using transcriptomic analysis of endothelial cells from CAD patients.
bioRxiv · Aug 18, 2025 · PreprintCell Biology