Mechanical activation of epithelial Na+ channel relies on an interdependent activity of the extracellular matrix and extracellular N-glycans of αENaC
Fenja Knoepp, Zoe Ashley, Daniel Barth, Marina Kazantseva, Pawel P. Szczesniak, Wolfgang G. Clauss, Mike Althaus, Diego Alvarez de la Rosa, Martin Fronius
The paper shows that ENaC channel activity in response to shear force depends on interactions with the extracellular matrix and N-glycans on the channel.
bioRxiv · Jan 25, 2017 · PreprintCell Biology