ImmunologybioRxiv
Monocyte-derived microglia with Dnmt3a mutation cause motor pathology in aging mice
Jung-Seok Kim, Sébastien Trzebanski, Sun-Hye Shin…·Steffen Jung
This study shows that monocyte-derived microglia with a Dnmt3a mutation cause motor deficits in aging mice, resembling Parkinsonian disorders.
DOI 10.1016/j.celrep.2025.115609