Author

Marino Exposito Rodriguez

AstraZeneca (United Kingdom)

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Synthetic Biology· 1

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Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

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Francesca CeroniiD· 1 shared Joshua Mayne· 1 shared Matthew R. Burrell· 1 shared Stephen GoldrickiD· 1 shared

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Francesca CeroniORCID

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Synthetic BiologybioRxivPreprintNov 10, 2025

Billion-Scale Deciphering of Human Gene Regulatory Grammar

Joshua Mayne, Marino Exposito Rodriguez, Matthew R. Burrell…·Stephen Goldrick

The paper introduces a scalable platform to generate large-scale sequence-to-expression datasets in human cells and trains deep learning models to predict gene expression from DNA sequences.

1 citation

humanDNA methylation

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