The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
Johanna Klughammer, Barbara Kiesel, Thomas Roetzer, Nikolaus Fortelny, Amelie Kuchler, Nathan C. Sheffield, Paul Datlinger, Nadine Peter, Karl-Heinz Nenning, Julia Furtner, Martha Nowosielski, Marco Augustin, Mario Mischkulnig, Thomas Ströbel, Patrizia Moser, , Christoph Bock
This study maps DNA methylation changes in glioblastoma tumors over time and space, revealing heterogeneity and links to tumor microenvironment and patient survival.
bioRxiv · Aug 9, 2017Cancer Biology