Author

Amelie Kuchler

Austrian Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christoph BockiD· 2 shared Johanna KlughammeriD· 2 shared Nathan C. SheffieldiD· 2 shared Paul DatlingeriD· 2 shared Adelheid Woehrer· 1 shared André F. RendeiroiD· 1 shared Anusha U. Saga· 1 shared Astrid E. Grams· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCancer Biology

Christoph BockORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DNA Methyltransferase 1 and 3a Expression in the Frontal Cortex Regulates Palatable Food Consumption

Mohan C. Manjegowda, Jonathan Joy-Gaba, Eric R. Wengert, Anusha U. Saga, Daniel M. Warthen, Amelie Kuchler, Ronald Petrus Albertus Gaykema, Manoj K. Patel, Nathan C. Sheffield, Michael M. Scott

This study shows that deleting DNA methyltransferase 1 and 3a in the mouse prefrontal cortex reduces palatable food consumption without affecting chow intake, with effects on neuron excitability and DNA methylation patterns.

bioRxiv · May 23, 2021 · PreprintNeuroscience

The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space

Johanna Klughammer, Barbara Kiesel, Thomas Roetzer, Nikolaus Fortelny, Amelie Kuchler, Nathan C. Sheffield, Paul Datlinger, Nadine Peter, Karl-Heinz Nenning, Julia Furtner, Martha Nowosielski, Marco Augustin, Mario Mischkulnig, Thomas Ströbel, Patrizia Moser, , Christoph Bock

This study maps DNA methylation changes in glioblastoma tumors over time and space, revealing heterogeneity and links to tumor microenvironment and patient survival.

bioRxiv · Aug 9, 2017Cancer Biology

Pooled CRISPR screening with single-cell transcriptome read-out

Paul Datlinger, André F. Rendeiro, Christian Schmidl, Thomas Krausgruber, Peter M. Traxler, Johanna Klughammer, Linda C. Schuster, Amelie Kuchler, Donát Alpár, Christoph Bock

This paper combines CRISPR genome editing with single-cell RNA sequencing to enable high-throughput screening with complex molecular read-outs.

Nature Methods · Jan 18, 2017Peer-reviewedGenomics