Author

Mark Germanos

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A Gabrielle van der Kraan· 1 shared Belinda YauiD· 1 shared Cedric S AsensioiD· 1 shared Christian Burns· 1 shared Hayley Webster· 1 shared Mark LaranceiD· 1 shared Melkam A KebedeiD· 1 shared Patricia Schwarzkopf· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

A Gabrielle van der Kraan

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1 paper

Recent·Most cited

VPS41 deletion triggers progressive loss of insulin stores and downregulation of beta-cell identity

Belinda Yau, Yousun An, Mark Germanos, Patricia Schwarzkopf, A Gabrielle van der Kraan, Mark Larance, Hayley Webster, Christian Burns, Cedric S Asensio, Melkam A Kebede

This study shows that VPS41 deletion causes insulin degradation and loss of beta-cell identity in mice, with lysosomal inhibition rescuing insulin content.

bioRxiv · Apr 17, 2024 · PreprintCell Biology