A rational approach for the targeted discovery and characterisation of microbiome-derived therapeutics
Lutz Krause, Joel A. Boyd, Charlotte Vivian, Annika Krueger, Jeimy Johana Jimenez Loayza, Johanna K. Ljungberg, Joyce Zhou, Andrea Rabellino, Bozica Nyeverecz, Michael D. Nissen, Kaylyn D. Tousignant, Mareike Bongers, Martha M. Cooper, Donovan H. Parks, Areej S. Alsheikh-Hussain, , Páraic Ó Cuív
This paper identifies microbiome-derived therapeutics for IBD using a metagenome-guided approach, showing improved disease markers and safety in preclinical models.
bioRxiv · Oct 22, 2024 · PreprintMicrobiology