Páraic Ó Cuív

This study shows that the microbiome in IBD patients has increased pro-inflammatory activity, even when microbial composition is similar to non-IBD controls.

This study identifies a bioactive compound from Enterococcus faecalis that suppresses IL-23 signaling and reduces inflammation in gut and joint diseases.

This study shows that a maternal high-fat diet increases neonatal systemic inflammation and predisposes to infant lung disease via neutrophil-mediated IL-6 trans-signaling.

This paper identifies microbiome-derived therapeutics for IBD using a metagenome-guided approach, showing improved disease markers and safety in preclinical models.