Assembly and activation of the AAA+ motor of the multi-subunit cobaltochelatase
Ana Cláudia Lyon de Moura, Benjamin Wiseman, Esra Bozkurt, Evelyne C. Deery, Richard W. Pickersgill, Amanda A. Brindley, Andrew Hitchcock, Martin Hoegbom, Martin J. Warren, Dmitry Shvarev
This study uses cryo-EM to determine the structure of the CobST cobaltochelatase motor and reveals how ATP and CobT regulate its assembly and activation for cobalt chelation.
bioRxiv · Oct 16, 2026 · PreprintBiochemistry