Proteomic and Kinetic Characterization of Prion Seeding in Distinct Human CJD Strains Unveils Early Diagnostic Biomarkers
Saima Zafar, Neelam Younas, Jean‐Yves Douet, Mathias Schmitz, Niccolò Candelise, Susana Correia, Olivier Andréoletti, Inga Zerr
The paper uses RT-QuIC and proteomics to analyze prion seeding activity and identify early diagnostic biomarkers in human CJD strains.
bioRxiv · Sep 17, 2025 · PreprintNeuroscience