Mutational landscape and molecular bases of echinocandin resistance in Saccharomyces cerevisiae
Romain Durand, Alexandre G. Torbey, Mathieu Giguere, Alicia Pageau, Alexandre K. Dubé, Patrick Lagüe, Christian R. Landry
The paper identifies key residues in Fks hotspots that confer echinocandin resistance in Saccharomyces cerevisiae using molecular dynamics and deep-mutational scanning.
Genetics · Mar 2, 2026Peer-reviewedMolecular Biology