High-Frequency Spinal Cord Stimulation Reorganizes Cortical Cross-Frequency Coupling in a Region- and Time-Dependent Manner
Vishal Bharmauria, Hiroyuki Oya, Yarema Bezchlibnyk, Nour Shaheen, Amirhossein Ghaderi, Yahia Yassine Belkacemi, Karim Johari, Arun Pratap Singh, Alexander L Green, Hiroto Kawasaki, Can Sarica, Brian Dalm, Andres M Lozano, Matthew A Howard, Oliver Flouty
This study shows high-frequency spinal cord stimulation changes cortical cross-frequency coupling in different brain regions and over time, with distinct effects in association and somatosensory cortices.
bioRxiv · Dec 17, 2025 · PreprintNeuroscience