Pathogenic DRP1 variants reveal a role for biomolecular condensation in mitochondrial fission
Kyle A. Ross, Amanda M. Travis, Megan Cleland Harwig, Micaela S. Young, Erica H Rodas Montejo, Matthew J Farah, Michael J Donohue, Robert William Taylor, Monika Oláhová, R. Blake Hill
This study shows pathogenic DRP1 variants impair mitochondrial fission by affecting biomolecular condensation, revealing a new regulatory mechanism.
bioRxiv · Oct 6, 2026 · PreprintBiophysics