Obesity Facilitates Sex-Specific Improvement In Cognition And Neuronal Function In A Rat Model Of Alzheimer's Disease
Aaron Y. Lai, Dustin Loren Almanza, Jessica A. Ribeiro, Mary Elizabeth Hill, Matthew Mandrozos, Margaret M. Koletar, Bojana Stefanovic, JoAnne McLaurin
This study shows obesity in early symptomatic AD rats improves cognition and myelin but worsens amyloid-beta and tau pathology, with stronger effects in females.
bioRxiv · Jan 11, 2024 · PreprintNeuroscience