Author

Maxwell A. Frye

Van Andel Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Darren J. MooreiD· 2 shared Erin T. WilliamsiD· 2 shared Alexis L. Bergsma· 1 shared Caio M. MassariiD· 1 shared Dylan J. Dues· 1 shared Jordan RowlandsiD· 1 shared Kayla A. Sipple· 1 shared Md. Shariful IslamiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Darren J. MooreORCID

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2 papers

Recent·Most cited

Parkinson's disease-linked D620N mutation selectively alters the brain-specific protein interactome of VPS35

Erin T. Williams, Maxwell A. Frye, Xi Chen, Jordan Rowlands, Md. Shariful Islam, Darren J. Moore

This study identifies a selective effect of the D620N VPS35 mutation on the brain-specific protein interactome in mammalian cells and brain tissue.

Neurobiology of Disease · Sep 1, 2026Peer-reviewedNeuroscience

Neuropathology in an α-synuclein preformed fibril mouse model occurs independent of the Parkinson's disease-linked lysosomal ATP13A2 protein

Caio M. Massari, Dylan J. Dues, Alexis L. Bergsma, Kayla A. Sipple, Maxwell A. Frye, Erin T. Williams, Darren J. Moore

This study shows that α-synuclein pathology spreads independently of ATP13A2 in a mouse model, indicating ATP13A2 is not critical for -syn clearance or propagation.

Neurobiology of Disease · Oct 13, 2024Peer-reviewedNeuroscience