DNAJB6 Isoform Specific Knockdown: Therapeutic Potential for LGMDD1
Andrew R. Findlay, May M. Paing, Jil Daw, Rocío Bengoechea, Sara K. Pittman, Shan Li, Feng Wang, Timothy M. Miller, Heather L. True, Tsui‐Fen Chou, Conrad Chris Weihl
This study investigates DNAJB6 isoform-specific knockdown as a potential therapy for LGMDD1, showing that reducing DNAJB6b levels in a mouse model corrected proteomic disease signatures.
bioRxiv · Nov 17, 2022 · PreprintNeuroscience