High-throughput heterospheroid-based screening identifies drugs that reprogram tumor-associated macrophages
Hiroyuki Tsuchiya, Takehiko Hanaki, Mayu Obora, Jun Yoshida, Mikiya Kishino, Yoshiyuki Fujiwara, Daisuke Nanba
This study identifies two compounds that reprogram tumor-associated macrophages from M2-like to M1-like antitumor phenotype using a heterospheroid-based screening platform.
Journal of Immunology Research · Jan 1, 2026Peer-reviewedPharmacology & Toxicology