Plasmalogen-Independent Neuroprotection: Synthetic alkyl ether lipids activate signaling to mitigate neuroinflammation and enhance cognitive function
Md. Shamim Hossain, MD Shalman Uddin Dipto, Masanori Honsho, Tatsuo Okauchi, Shiro Mawatari, Takehiko Fujino
This study shows that synthetic alkyl ether lipids like KIT-8 reduce neuroinflammation and improve memory in mice without requiring plasmalogen synthesis.
bioRxiv · Dec 11, 2025 · PreprintNeuroscience