PIWIL3-piRNA Pathway Is Essential for Rabbit Oogenesis and Embryogenesis via Broad Regulation of the Transcriptome and Proteome
Yuanyuan Gong, Ling Li, Yuqiang Qian, Ting Lu, Zhaoran Zhang, Lichun Jiang, Guohui Liu, Meihua Cui, Shangang Li, Zhanjun Li, Shuo Shi, Haifan Lin
This study shows that PIWIL3 is essential for rabbit oogenesis and embryogenesis by regulating transcriptome and proteome, with implications for human fertility.
bioRxiv · Oct 23, 2025 · PreprintDevelopmental Biology